Archer™ VARIANTPlex™ AML Focus panel

产品详情

 

The Archer™ VARIANTPlex™ AML Focus panel can identify key single nucleotide variants, internal tandem duplications, insertions, and deletions with targeted NGS of 11 core genes relevant for acute myeloid leukemia (AML) research.

 

 

Specifications

Targeted genes

11

Genomic alterations

SNVs, Indels, ITDs

Input nucleic acid required*

≥10 ng

Recommended number of reads

800 K

Hands-on time

<3.5 hours

Total library prep time

1.5 days

Platform compatibility

Illumina®

Reagent format

Lyophilized or liquid

Supported sample types

Blood, bone marrow, fresh frozen, FFPE, BMMC, PBMC

 

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

 

 

基因靶标

 

 

 

产品优势

 

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Detect confidently—A unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, one of the many ways that Archer Analysis empowers you to detect confidently.

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Less QNS—Anchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and degraded samples such as FFPE tissue.

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Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.

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Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.

 

 

产品资料

 

VARIANTPlex-HT Protocol for Illumina

VARIANTPlex HS-HGC Protocol for Illumina

VARIANTPlex-HT AML Focus Panel Product Insert

VARIANTPlex AML Focus Product Insert