Archer™ VARIANTPlex™ Pan Solid Tumor panel - 锚定多重PCR

产品详情

The Archer™ VARIANTPlex™ Pan Solid Tumor panel can Efficiently detect single nucleotide variants, copy number variations, insertions, and deletions by targeted NGS of 185 genes along with microsatellite instability, tumor mutational burden, and homologous recombination deficiency status relevant for colorectal, breast, melanoma, gastric, pancreatic, CNS, NSCLC, and other pan-cancer research.

The VARIANTPlex Pan Solid Tumor v2 panel is available with integrated HRD assessment. The VARIANTPlex Pan Solid Tumor v1 panel can be paired with the VARIANTPlex HRD Module to provide an HRD assessment on a by-sample basis.

	VARIANTPlex Pan Solid Tumor v1 panel	VARIANTPlex Pan Solid Tumor v2 panel
Targeted genes	185	185
Genomic alterations	SNVs, Indels, CNVs, ITDs, MSI, TMB	SNVs, Indels, CNVs, ITDs, MSI, TMB, HRD
Input nucleic acid required*	≥10 ng	≥10 ng
Recommended number of reads	25 M	37 M
Hands-on time	<3.5 hours	<3.5 hours
Total library prep time	1.5 days	1.5 days
Platform compatibility	Illumina®	Illumina®
Reagent format	Lyophilized or liquid	Lyophilized or liquid
Supported sample types	FFPE, fresh frozen, cytology smear, FNA	FFPE, fresh frozen, cytology smear, FNA

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

基因靶标

产品优势

●	Flexible, customizable insights—Combine pre-designed panels, create custom panel content, and easily add targets to your existing assay, while maintaining high performance with minimal workflow disruption.
●	Detect confidently—Anchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and potentially degraded samples such as FFPE tissue. Archer Analysis includes a unique outlier detection algorithm that leverages position-specific data to enable variant detection even at low allele frequencies, empowering you to detect confidently.
●	Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.

产品资料

VARIANTPlex-HT Protocol for Illumina

VARIANTPlex HS-HGC Protocol for Illumina

VARIANTPlex-HT Pan Solid Tumor v2 Product Insert

VARIANTPlex Pan Solid Tumor v2 Product Insert