xGen™ Lynch Syndrome Amplicon Panel

A multigene panel to identify mutations in DNA Mismatch Repair (MMR) genes with comprehensive and exon-level hotspot coverage of 4 clinically-relevant genes: MLH1, MSH2, MSH6, and PMS2. And with sensitivity down to 1% allele frequency to identify both germline and somatic mutations in the same panel.

 

 

Feature

xGen Lynch Syndrome Amplicon Panel

Amplicons

180

Amplicon Size

116–150 (Average 139 bp)

Number of Genes

4

Genes List

MLH1, MSH2, MSH6, PMS2

Total Target

15 kb

Input Recommended

~10 ng

Time Required

2.5 hours from DNA-to-libraries

Limit of Detection

>1%

Sample Compatibility

Cell line, whole blood, cfDNA, FFPE

Multiplexing on MiSeq® v2 at 5000X Depth

33

 

 

 

 

订购信息

 

xGen™ Amplicon Core Kit

Product

Catalog #

xGen™ Amplicon Core 96rxn

10009827

 

xGen™ Oncology Amplicon Panels

Product

Catalog #

xGen™ Lynch Syndrome Amplicon Panel96rxn

10009835